IL-17 (Interleukin-17) antibody

Details for Product No. ABIN2474946
Antigen
  • CTLA8
  • IL-17
  • IL-17A
  • IL17
  • Ctla-8
  • Ctla8
  • Il17
  • ChIL-17
  • IL-17F
  • IL17A
  • CTLA-8
  • interleukin 17A
  • IL17A
  • Il17a
Reactivity
Mouse (Murine)
91
54
32
10
9
5
5
4
3
2
2
1
Host
Rat
93
39
15
13
8
2
1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
19
10
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
Application
Flow Cytometry (FACS), ELISA, Western Blotting (WB)
119
91
40
26
26
22
19
18
17
14
13
6
2
2
2
2
2
1
1
Options
Clone TC11-18H10
Isotype IgG1
Specificity This antibody recognises mouse Interleukin 17, a 32 kDa disulfide-linked homodimer consisting of two 136 amino acid chains, which belong to the IL-17 family (classified as IL-17A to IL-17F), and signal through the IL-17 receptor (IL-17R/CDw217). IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction.
Characteristics Purified IgG
Purification Purified
Antigen
Alternative Name IL-17
Background Synonyms: IL-17A
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Did you look for something else?