Tim-1 antibody (PE)

Details for Product No. ABIN2476813
Antigen
  • Tim1
  • Rho guanine nucleotide exchange factor 5
  • Arhgef5
Reactivity
Mouse (Murine)
25
11
4
Host
Rat
19
7
5
2
Clonality (Clone)
Monoclonal ()
Conjugate
PE
2
2
1
Application
Flow Cytometry (FACS)
26
17
10
8
4
1
1
Options
Immunogen Full-length mouse Tim-1-Ig, containing both the IgV and mucin domains of Tim-1.
Clone RMT1-10
Isotype IgG2a
Characteristics Purified IgG conjugated to R. Phycoerythrin (RPE)
Antigen
Background Synonyms: T-CELL IMMUNOGLOBULIN MUCIN 1
Gene ID 171283
UniProt Q5QNS5
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Supplier Images
Image no. 1 for anti-Tim-1 antibody (PE) (ABIN2476813) anti-Tim-1 antibody (PE)
Product cited in: Freeman, Casasnovas, Umetsu, DeKruyff: "TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity." in: Immunological reviews, Vol. 235, Issue 1, pp. 172-89, 2010 (PubMed).

Yuan, Ansari, DAddio, Paez-Cortez, Schmitt, Donnarumma, Boenisch, Zhao, Popoola, Clarkson, Yagita, Akiba, Freeman, Iacomini, Turka, Glimcher, Sayegh: "Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 26, pp. 10734-9, 2009 (PubMed).

Xiao, Najafian, Reddy, Albin, Zhu, Jensen, Imitola, Korn, Anderson, Zhang, Gutierrez, Moll, Sobel, Umetsu, Yagita, Akiba, Strom, Sayegh, DeKruyff, Khoury, Kuchroo: "Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function." in: The Journal of experimental medicine, Vol. 204, Issue 7, pp. 1691-702, 2007 (PubMed).

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