Transferrin antibody (N-Term)
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- Target See all Transferrin (TF) Antibodies
- Transferrin (TF)
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Pig, Rabbit
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Transferrin antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Functional Studies (Func)
- Specificity
- Anti transferrin clone HTF-14 is specific for the N-terminal domain of human transferrin and has been shown to block binding of transferrin to the transferrin receptor (CD71). Clone HTF-14 is not able to recognise receptor bound transferrin. Clone HTF-14 recognises a conformational epitope in a loop of the N lobe of transferrin involving the critical Lys-144 residue, also essential for binding of the N lobe to the transferrin receptor (Mason et al.2009)Transferrin is a 77 kDa plasma protein synthesized by the liver involved with the transport of iron. Each transferrin molecule has two domains, both with facility to carry 2 ferric ions. The iron/transferrin complex is essential for haemoglobin synthesis and certain types of cell division.
- Cross-Reactivity
- Pig (Porcine), Rabbit, Rat (Rattus)
- Characteristics
- Purified IgG
- Purification
- Purified
- Immunogen
- Purified porcine transferrin
- Clone
- HTF-14
- Isotype
- IgG1
- Top Product
- Discover our top product TF Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
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- Target
- Transferrin (TF)
- Alternative Name
- TRANSFERRIN (TF Products)
- Gene ID
- 7018
- UniProt
- P02787
- Pathways
- Transition Metal Ion Homeostasis
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