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Transferrin antibody (N-Term)

TF Reactivity: Human, Rat, Pig, Rabbit WB, ELISA, IF, Func Host: Mouse Monoclonal HTF-14 unconjugated
Catalog No. ABIN2476916
  • Target See all Transferrin (TF) Antibodies
    Transferrin (TF)
    Binding Specificity
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 139
    • 37
    • 35
    • 33
    • 13
    • 13
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    Human, Rat, Pig, Rabbit
    Host
    • 154
    • 58
    • 23
    • 14
    • 4
    Mouse
    Clonality
    • 190
    • 59
    • 1
    Monoclonal
    Conjugate
    • 137
    • 37
    • 32
    • 11
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Transferrin antibody is un-conjugated
    Application
    • 162
    • 89
    • 68
    • 46
    • 41
    • 31
    • 30
    • 22
    • 22
    • 20
    • 16
    • 16
    • 13
    • 12
    • 9
    • 9
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Functional Studies (Func)
    Specificity
    Anti transferrin clone HTF-14 is specific for the N-terminal domain of human transferrin and has been shown to block binding of transferrin to the transferrin receptor (CD71). Clone HTF-14 is not able to recognise receptor bound transferrin. Clone HTF-14 recognises a conformational epitope in a loop of the N lobe of transferrin involving the critical Lys-144 residue, also essential for binding of the N lobe to the transferrin receptor (Mason et al.2009)Transferrin is a 77 kDa plasma protein synthesized by the liver involved with the transport of iron. Each transferrin molecule has two domains, both with facility to carry 2 ferric ions. The iron/transferrin complex is essential for haemoglobin synthesis and certain types of cell division.
    Cross-Reactivity
    Pig (Porcine), Rabbit, Rat (Rattus)
    Characteristics
    Purified IgG
    Purification
    Purified
    Immunogen
    Purified porcine transferrin
    Clone
    HTF-14
    Isotype
    IgG1
    Top Product
    Discover our top product TF Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
  • Target
    Transferrin (TF)
    Alternative Name
    TRANSFERRIN (TF Products)
    Gene ID
    7018
    UniProt
    P02787
    Pathways
    Transition Metal Ion Homeostasis
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