T and B cell Activation Marker antibody (Pacific Blue)
Reactivity: Human, Mouse
FACS, CyTOF
Host: Rat
Monoclonal
GL7
Pacific Blue
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- Target
- T and B cell Activation Marker
- Reactivity
- Human, Mouse
- Host
- Rat
- Clonality
- Monoclonal
- Conjugate
- Pacific Blue
- Application
- Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)
- Characteristics
- The GL7 antigen, also known as Ly77, is a 35 kD protein. The GL7 antigen has an epitope containing non-sulfated α 2-6-sialyl-LacNAc recognized by the GL7 antibody. The GL7 antigen is expressed by pre-B and immature B cells, activated T and B cells, and about 20 % of TCR-bright thymocytes. It is upregulated on mouse splenocytes following activation. It may play a role in regulation or adhesion. GL7 high-expressing B cells show higher antibody production and antigen presenting capacity.
- Purification
- The antibody was purified by affinity chromatography and conjugated with Pacific Blue™ under optimal conditions. The solution is free of unconjugated Pacific Blue™.
- Clone
- GL7
- Isotype
- IgM kappa
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Protect from prolonged exposure to light. Do not freeze.
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- T and B cell Activation Marker
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