ATG12 antibody (Middle Region)
-
- Target See all ATG12 Antibodies
- ATG12 (Autophagy Related 12 (ATG12))
-
Binding Specificity
- Middle Region
-
Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This ATG12 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- KFLKLVASEQ LFIYVNQSFA PSPDQEVGTL YECFGSDGKL VLHYCKSQAW
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against ATG12. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ATG12
- Top Product
- Discover our top product ATG12 Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 187 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- ATG12 (Autophagy Related 12 (ATG12))
- Alternative Name
- ATG12 (ATG12 Products)
- Background
-
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).
Alias Symbols: APG12, APG12L, FBR93, HAPG12
Protein Interaction Partner: CRX, WIPI2, FADD, EXOC4, Atg10, ATG3, ATG5, CAV1, ATG16L1, WDFY3, APP, BCL2, MCL1, TECPR1, UBC, ATG7, ATG4B, GABARAP, MAP1B, KRTAP4-12, PLSCR1, MDFI, PTK2, DHX36, OTUD4, SF3B1, SF3A1, AUP1,
Protein Size: 187 - Molecular Weight
- 21 kDa
- Gene ID
- 9140
- NCBI Accession
- NM_004707, NP_004698
- UniProt
- O94817
- Pathways
- Autophagy
-