ZFP36 antibody (N-Term)

Catalog No. ABIN2775764

Product Details anti-ZFP36 Antibody

Target: ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFP36 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PLAPRLGPEL SPSPTSPTAT STTPSRYKTE LCRTFSESGR CRYGAKCQFA

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against ZFP36. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZFP36

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 326 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ZFP36 antibody (ABIN2775764)

Marti, Zurfluh, Hagens, Pianezzi, Klumpp, Loessner: "Long tail fibres of the novel broad-host-range T-even bacteriophage S16 specifically recognize Salmonella OmpC." in: Molecular microbiology, Vol. 87, Issue 4, pp. 818-34, (2013) (PubMed).

Fähling, Persson, Klinger, Benko, Steege, Kasim, Patzak, Persson, Wolf, Blüthgen, Mrowka: "Multilevel regulation of HIF-1 signaling by TTP." in: Molecular biology of the cell, Vol. 23, Issue 20, pp. 4129-41, (2012) (PubMed).

Target Details for ZFP36

Target: ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))

Alternative Name: ZFP36 (ZFP36 Products)

Background: Located on chromosome 19, ZFP36 encodes a protein that is involved in controlling pro-inflammatory cytokines.
Alias Symbols: TTP, G0S24, GOS24, TIS11, NUP475, RNF162A
Protein Interaction Partner: YWHAB, PPP2CA, DNAJB1, DCP1B, DHX36, PRR5L, XRN1, UBC, TRAF2, EXOSC6, UPF2, EXOSC8, YWHAQ, TNF, DCP2, EDC3, DCP1A, EDC4, CDK6, APP, LIN28A, SH3KBP1, PABPC1, NCL, MAP3K4, HSPA4, HDAC7, HDAC3, NFKB1, HOXC9, HDAC1, CCDC85B, MAPKAPK2, YWHAG, SFN, HMGB1, NUP21
Protein Size: 326

Molecular Weight: 34 kDa

Gene ID: 7538

NCBI Accession: NM_003407, NP_003398

UniProt: P26651