Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 7 (KCNA7) (C-Term) antibody

Details for Product No. ABIN2776260
Antigen
  • hak6
  • kv1.7
  • XKv1.10
  • kvl10-A
  • HAK6
  • KV1.7
  • Kv1.7
  • potassium channel, voltage gated shaker related subfamily A, member 7 S homeolog
  • potassium voltage-gated channel subfamily A member 7
  • potassium voltage-gated channel, shaker-related subfamily, member 7
  • kcna7.S
  • KCNA7
  • Kcna7
Epitope
C-Term
7
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Human, Mouse (Murine), Rat (Rattus)
19
12
3
Host
Rabbit
20
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
1
Application
Western Blotting (WB)
11
8
8
2
1
1
1
Options
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human KCNA7
Blocking Peptide Blocking peptide for this product available: ABIN978749
Sequence GEEAGMFSHV DMQPCGPLEG KANGGLVDGE VPELPPPLWA PPGKHLVTEV
Predicted Reactivity Cow: 79%, Dog: 86%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against KCNA7. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Antigen
Alternative Name KCNA7 (KCNA7 Antibody Abstract)
Background Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, e
Alias Symbols: HAK6, KV1.7
Protein Size: 456
Molecular Weight 50 kDa
Gene ID 3743
NCBI Accession NM_031886, NP_114092
UniProt Q96RP8
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 456 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 7 (KCNA7) (C-Term) antibody (ABIN2776260) WB Suggested Anti-KCNA7 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Po...
Product cited in: Cherpes, Kusne, Hillier: "Haemophilus influenzae septic abortion." in: Infectious diseases in obstetrics and gynecology, Vol. 10, Issue 3, pp. 161-4, 2003 (PubMed).

Background publications Bardien-Kruger, Wulff, Arieff, Brink, Chandy, Corfield: "Characterisation of the human voltage-gated potassium channel gene, KCNA7, a candidate gene for inherited cardiac disorders, and its exclusion as cause of progressive familial heart block I (PFHBI)." in: European journal of human genetics : EJHG, Vol. 10, Issue 1, pp. 36-43, 2002 (PubMed).

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