Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 7 (KCNH7) (N-Term) antibody

Details for Product No. ABIN2776316
Antigen
  • KCNH7
  • kcnh7
  • ERG3
  • HERG3
  • Kv11.3
  • 9330137I11Rik
  • erg3
  • potassium voltage-gated channel subfamily H member 7
  • potassium channel, voltage gated eag related subfamily H, member 7
  • potassium voltage-gated channel, subfamily H (eag-related), member 7
  • KCNH7
  • kcnh7
  • LOC100545485
  • Kcnh7
Epitope
N-Term
10
9
8
4
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
48
22
20
3
3
3
3
2
2
2
2
1
Host
Rabbit
48
Clonality
Polyclonal
Conjugate
Un-conjugated
4
3
3
2
2
2
1
1
1
1
1
1
Application
Western Blotting (WB)
36
25
25
16
5
1
1
Options
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human KCNH7
Blocking Peptide Blocking peptide for this product available: ABIN978779
Sequence PILPIKTVNR KFFGFKFPGL RVLTYRKQSL PQEDPDVVVI DSSKHSDDSV
Predicted Reactivity Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against KCNH7. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Antigen
Alternative Name KCNH7 (KCNH7 Antibody Abstract)
Background Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNH7 is a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms.
Alias Symbols: ERG3, HERG3, Kv11.3, MGC45986
Protein Size: 732
Molecular Weight 83 kDa
Gene ID 90134
NCBI Accession NM_173162, NP_775185
UniProt Q8IV15
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 732 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 7 (KCNH7) (N-Term) antibody (ABIN2776316) WB Suggested Anti-KCNH7 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Posi...
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