WNT7B antibody (Middle Region)

Catalog No. ABIN2776732

Product Details anti-WNT7B Antibody

Target: WNT7B (Wingless-Type MMTV Integration Site Family, Member 7B (WNT7B))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNT7B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: WTTLPKFREV GHLLKEKYNA AVQVEVVRAS RLRQPTFLRI KQLRSYQKPM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against WNT7B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human WNT7B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 349 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-WNT7B antibody (ABIN2776732)

Gore, Deitz, Palam, Craven, Korc: "Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-β to promote proliferation." in: The Journal of clinical investigation, Vol. 124, Issue 1, pp. 338-52, (2014) (PubMed).

Target Details for WNT7B

Target: WNT7B (Wingless-Type MMTV Integration Site Family, Member 7B (WNT7B))

Alternative Name: WNT7B (WNT7B Products)

Background: This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fat
Alias Symbols: -
Protein Interaction Partner: CASK, CUL3, TCEB1, PORCN, GPC3,
Protein Size: 349

Molecular Weight: 36 kDa

Gene ID: 7477

NCBI Accession: NM_058238, NP_478679

UniProt: P56706

Pathways: WNT Signaling