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SF3A3 antibody (Middle Region)

SF3A3 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Pubmed (1 reference)
Catalog No. ABIN2779010
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  • Target See all SF3A3 Antibodies
    SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 20
    • 15
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)
    Host
    • 19
    • 2
    Rabbit
    Clonality
    • 18
    • 3
    Polyclonal
    Conjugate
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SF3A3 antibody is un-conjugated
    Application
    • 12
    • 7
    • 6
    • 6
    • 3
    • 2
    Western Blotting (WB)
    Sequence
    THENVQRKQA RTGEEREEEE EEQISESESE DEENEIIYNP KNLPLGWDGK
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 91%
    Characteristics
    This is a rabbit polyclonal antibody against SF3A3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SF3A3
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 501 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • Target
    SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))
    Alternative Name
    SF3A3 (SF3A3 Products)
    Synonyms
    PRP9 antibody, PRPF9 antibody, SAP61 antibody, SF3a60 antibody, 4930512K19Rik antibody, 60kDa antibody, LRRGT00093 antibody, wu:fi15a06 antibody, wu:fj94f01 antibody, zgc:110227 antibody, splicing factor 3a subunit 3 antibody, splicing factor 3a, subunit 3, 60kDa antibody, splicing factor 3a, subunit 3 antibody, splicing factor 3a subunit 3 S homeolog antibody, SF3A3 antibody, Sf3a3 antibody, sf3a3.S antibody, sf3a3 antibody
    Background
    SF3A3 is the subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP.This This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: PRP9, PRPF9, SAP61, SF3a60
    Protein Interaction Partner: TRIM69, HUWE1, ZNF212, TADA2A, FUS, UBC, NEDD8, MDM2, WWOX, RNF2, SUZ12, EED, rev, APBB1, ACTN1, ACTN4, STAM2, HGS, SNRPB, CDAN1, PRPF40A, WBP4, TCERG1, UBD, SF3A1, FN1, gag-pol, PRMT5, PRPF19, PRPF31, SF3B1, SF3B3, SF3B4, HNRNPR, DDX46, TOX4, DDX23, PRPF
    Protein Size: 501
    Molecular Weight
    59 kDa
    Gene ID
    10946
    NCBI Accession
    NM_006802, NP_006793
    UniProt
    Q12874
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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