TFAP2C antibody (N-Term)

Catalog No. ABIN2780497

Product Details anti-TFAP2C Antibody

Target: TFAP2C (Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Rabbit, Pig, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFAP2C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MLWKITDNVK YEEDCEDRHD GSSNGNPRVP HLSSAGQHLY SPAPPLSHTG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 75%, Horse: 75%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against TFAP2C. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TFAP2C

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 450 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TFAP2C

Target: TFAP2C (Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C))

Alternative Name: TFAP2C (TFAP2C Products)

Background: TFAP2C is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube.The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube.
Alias Symbols: AP2-GAMMA, ERF1, TFAP2G, hAP-2g
Protein Interaction Partner: ZFAND4, NR1I2, IKBKB, GPR22, CCNG1, KCTD1, SUMO1, UBE2I, BRCA1, HHV8GK18_gp81, KDM5B, MYC, ELAVL1, SUMO2, UBC, CITED4, CITED2, CITED1, TP53,
Protein Size: 450

Molecular Weight: 49 kDa

Gene ID: 7022

NCBI Accession: NM_003222, NP_003213

UniProt: Q92754

Pathways: Stem Cell Maintenance