ACD antibody (Middle Region)

Catalog No. ABIN2787609

Product Details anti-ACD Antibody

Target: ACD (Adrenocortical Dysplasia Homolog (ACD))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACD antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KNRPPFPRTG ATRGAQEPCS VWEPPKRHRD GSAFQYEYEP PCTSLCARVQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ACD. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ACD

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 544 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ACD

Target: ACD (Adrenocortical Dysplasia Homolog (ACD))

Alternative Name: ACD (ACD Products)

Synonyms: PIP1 antibody, PTOP antibody, TINT1 antibody, TPP1 antibody, ACD antibody, ACD, shelterin complex subunit and telomerase recruitment factor antibody, adrenocortical dysplasia antibody, ACD antibody, Acd antibody

Background: ACD is a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other comp
Alias Symbols: PIP1, PTOP, TINT1, TPP1
Protein Interaction Partner: TINF2, ANXA8L1, POT1, USP7, CUL5, ZNF790, PAGE2, APOBEC3F, NUDCD2, LRRC25, TRIM15, AFAP1L2, TBC1D10A, PDLIM2, RBKS, ANKMY2, PGM2, SBDS, LGALSL, DBNL, AIPL1, NCDN, STIP1, TOMM34, NUDC, TRIM16, TUBB4B, STUB1, FAM131B, BAG3, RECQL4, EIF3G, FKBP6, YWHAE, TUBB
Protein Size: 544

Molecular Weight: 58 kDa

Gene ID: 65057

NCBI Accession: NM_001082486, NP_001075955

UniProt: Q96AP0

Pathways: Telomere Maintenance