ACD antibody (Adrenocortical Dysplasia Homolog (Mouse)) (C-Term)

Details for Product anti-ACD Antibody No. ABIN2787610
Target
Binding Specificity
C-Term
5
4
2
1
1
1
1
1
1
1
1
Reactivity
Human
36
13
8
3
3
3
3
1
Host
Rabbit
24
8
7
Clonality
Polyclonal
Conjugate
This ACD antibody is un-conjugated
3
2
2
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
31
17
6
4
4
3
2
2
1
Options
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human ACD
Blocking Peptide Blocking peptide for this product available: ABIN972808
Sequence SSQPSPAICS APATLTPRSP HASRTPSSPL QSCTPSLSPR SHVPSPHQAL
Predicted Reactivity Human: 100%
Characteristics This is a rabbit polyclonal antibody against ACD. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Target
Alternative Name ACD (ACD Antibody Abstract)
Background ACD is a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere.This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.
Alias Symbols: PIP1, PTOP, TINT1, TPP1
Protein Interaction Partner: TINF2, ANXA8L1, POT1, USP7, CUL5, ZNF790, PAGE2, APOBEC3F, NUDCD2, LRRC25, TRIM15, AFAP1L2, TBC1D10A, PDLIM2, RBKS, ANKMY2, PGM2, SBDS, LGALSL, DBNL, AIPL1, NCDN, STIP1, TOMM34, NUDC, TRIM16, TUBB4B, STUB1, FAM131B, BAG3, RECQL4, EIF3G, FKBP6, YWHAE, TUBB
Protein Size: 544
Molecular Weight 58 kDa
Gene ID 65057
NCBI Accession NM_001082486, NP_001075955
UniProt Q96AP0
Pathways Telomere Maintenance
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 544 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Images
Image no. 1 for anti-Adrenocortical Dysplasia Homolog (Mouse) (ACD) (C-Term) antibody (ABIN2787610) WB Suggested Anti-ACD Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Con...