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ACD antibody (Adrenocortical Dysplasia Homolog (Mouse)) (C-Term) Primary Antibody

ACD Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2787610
$389.00
Plus shipping costs $45.00
100 μL
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  • Target
    ACD
    Binding Specificity
    C-Term
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Reactivity
    Human
    • 36
    • 13
    • 8
    • 3
    • 3
    • 3
    • 3
    • 1
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    This ACD antibody is un-conjugated
    • 23
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Western Blotting (WB)
    • 31
    • 17
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Sequence
    SSQPSPAICS APATLTPRSP HASRTPSSPL QSCTPSLSPR SHVPSPHQAL
    Predicted Reactivity
    Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against ACD. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human ACD
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 544 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ACD
    Alternative Name
    ACD (ACD Antibody Abstract)
    Synonyms
    PIP1, PTOP, TINT1, TPP1, ACD, ACD, shelterin complex subunit and telomerase recruitment factor, adrenocortical dysplasia, ACD, Acd
    Background
    ACD is a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere.This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.
    Alias Symbols: PIP1, PTOP, TINT1, TPP1
    Protein Interaction Partner: TINF2, ANXA8L1, POT1, USP7, CUL5, ZNF790, PAGE2, APOBEC3F, NUDCD2, LRRC25, TRIM15, AFAP1L2, TBC1D10A, PDLIM2, RBKS, ANKMY2, PGM2, SBDS, LGALSL, DBNL, AIPL1, NCDN, STIP1, TOMM34, NUDC, TRIM16, TUBB4B, STUB1, FAM131B, BAG3, RECQL4, EIF3G, FKBP6, YWHAE, TUBB
    Protein Size: 544
    Molecular Weight
    58 kDa
    Gene ID
    65057
    NCBI Accession
    NM_001082486, NP_001075955
    UniProt
    Q96AP0
    Pathways
    Telomere Maintenance
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