HSP90AB1 antibody (N-Term)

Catalog No. ABIN970914

Product Details anti-HSP90AB1 Antibody

Target: HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSP90AB1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NASDALDKIR YESLTDPSKL DSGKELKIDI IPNPQERTLT LVDTGIGMTK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against Hsp90ab1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 724 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HSP90AB1

Target: HSP90AB1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class B Member 1 (HSP90AB1))

Alternative Name: Hsp90ab1 (HSP90AB1 Products)

Background: Hsp90ab1 is a molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
Alias Symbols: 90 kDa, AL022974, C81438, Hsp84, Hsp84-1, Hsp90, Hspcb, MGC115780
Protein Interaction Partner: Isg15, Htt, HACE1, DNAJB2, Eed, Akt1, Hsp90ab1, Hsf1, Hdac6, UBQLN1, DSK2, Itgb1bp2, Mapk7, Pgr, Nr3c1, Vcp, CALM1, Stub1, Ptges3, Mks1, Iqcb1, Nphp4, Nphp1, Ahi1, Invs, CFTR, Nod2, Nr3c2, Nr1i3, Irf3, Ip6k2, PRKACB, Cdkn2a, Gcgr, Nod1, Chordc1, Slc34a1,
Protein Size: 724

Molecular Weight: 83 kDa

Gene ID: 15516

NCBI Accession: NM_008302, NP_032328

UniProt: P11499

Pathways: Regulation of Cell Size