SLC22A5 antibody (C-Term)

Catalog No. ABIN2789486

Product Details anti-SLC22A5 Antibody

Target: SLC22A5 (Solute Carrier Family 22 Member 5 (SLC22A5))

Binding Specificity: C-Term

Reactivity: Human, Rat, Cow, Horse, Guinea Pig, Dog, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC22A5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GIVVPSTIFD PSELQDLSSK KQQSHNILDL LRTWNIRMVT IMSIMLWMTI

Predicted Reactivity: Cow: 100%, Dog: 85%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against SLC22A5. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 557 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLC22A5

Target: SLC22A5 (Solute Carrier Family 22 Member 5 (SLC22A5))

Alternative Name: SLC22A5 (SLC22A5 Products)

Background: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy.
Alias Symbols: CDSP, FLJ46769, OCTN2, OCTN2VT
Protein Interaction Partner: UBC, ELAVL1, PDZD3, SLC9A3R2, SLC9A3R1, PDZK1,
Protein Size: 557

Molecular Weight: 61 kDa

Gene ID: 6584

NCBI Accession: NM_003060, NP_003051

UniProt: O76082