DEF6 antibody (C-Term)

Catalog No. ABIN2790081

Product Details anti-DEF6 Antibody

Target: DEF6 (Differentially Expressed in FDCP 6 Homolog (DEF6))

Binding Specificity: C-Term

Reactivity: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEF6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SSSFSGFQPP LLAHRDSSLK RLTRWGSQGN RTPSPNSNEQ QKSLNGGDEA

Predicted Reactivity: Cow: 79%, Dog: 86%, Guinea Pig: 83%, Horse: 79%, Human: 100%, Pig: 86%, Rabbit: 79%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against DEF6. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DEF6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 631 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DEF6

Target: DEF6 (Differentially Expressed in FDCP 6 Homolog (DEF6))

Alternative Name: DEF6 (DEF6 Products)

Background: DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC and CDC42 that is highly expressed in B and T cells.
Alias Symbols: IBP, SLAT, SWAP70L
Protein Interaction Partner: HOMEZ, PBXIP1, EIF4ENIF1, CDC42EP1, TCF4, PTK2, PLSCR1, UBC, APP, BEGAIN, RAC2, RAC1, ZAP70, RHOA, LCK, CDC42,
Protein Size: 631

Molecular Weight: 74 kDa

Gene ID: 50619

NCBI Accession: NM_022047, NP_071330

UniProt: Q9H4E7