INTU antibody (C-Term)

Catalog No. ABIN2790639

Product Details anti-INTU Antibody

Target: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Binding Specificity: C-Term

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTU antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TLEEVAQLSG SIHPQLIKNF HQCCLSIRAV FQQTLVEEKK KGLNSGDHSD

Predicted Reactivity: Dog: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against INTU. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human INTU

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 942 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for INTU

Target: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Alternative Name: INTU (INTU Products)

Synonyms: 9230116I04Rik antibody, 9430087H23Rik antibody, Pdzd6 antibody, Pdzk6 antibody, mKIAA1284 antibody, INT antibody, PDZD6 antibody, PDZK6 antibody, Xint antibody, in antibody, int antibody, pdzd6 antibody, inturned planar cell polarity protein antibody, inturned planar cell polarity protein S homeolog antibody, Intu antibody, INTU antibody, intu antibody, intu.S antibody

Background: INTU plays a key role in ciliogenesis and embryonic development. INTU is a regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. It plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension and has an indirect effect on hedgehog signaling.
Alias Symbols: FLJ41326, INT, KIAA1284, PDZD6, PDZK6
Protein Size: 942

Molecular Weight: 104 kDa

Gene ID: 27152

NCBI Accession: NM_015693, NP_056508

UniProt: Q9ULD6