LRFN2 antibody (AA 401-500) (AbBy Fluor® 594)

Catalog No. ABIN2803838

Product Details anti-LRFN2 Antibody (AbBy Fluor® 594)

Target: LRFN2 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 2 (LRFN2))

Binding Specificity: AA 401-500

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRFN2 antibody is conjugated to AbBy Fluor® 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LRFN2/SALM1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LRFN2

Target: LRFN2 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 2 (LRFN2))

Alternative Name: LRFN2/SALM1 (LRFN2 Products)

Background:

Synonyms: leucine rich repeat and fibronectin type III domain containing 2, RP11-535K1.2, fibronectin type III, immunoglobulin and leucine rich repeat domains 2 antibody FIGLER2, Leucine-rich repeat and fibronectin type-III domain-containing protein 2, LRFN2, LRFN2_HUMAN, SALM1, Synaptic adhesion-like molecule 1.

Background: LRFN2 is a 789 amino acid single-pass type I membrane protein belonging to the LRFN family. Encoded by a gene that maps to human chromosome 6p21.2, LRFN2 is moderately expressed in brain, spleen and testis. LRFN2 contains one fibronectin type-III domain, one Ig-like (immunoglobulin-like) domain and six LRR (leucine-rich) repeats. LRFN2 promotes neurite outgrowth in hippocampal neurons, enhances cell surface expression of two NMDA receptor subunits, NMDA1 and NMDA?1, and may play a role in redistributing PSD-95 to cell periphery. LRFN2 forms heteromeric complexes with LRFN1, LRFN3, LRFN4 and LRFN5, and is capable of forming homomeric complexes, but not across cell junctions.

Pathways: Synaptic Membrane