Chromosome 22 Open Reading Frame 28 (C22orf28) antibody (Alexa Fluor 594)

Details for Product No. ABIN2810778
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
50
30
28
4
4
4
4
4
4
3
2
2
2
2
2
1
1
Host
Rabbit
42
13
Clonality
Polyclonal
Conjugate
Alexa Fluor 594
5
5
5
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
36
26
12
6
5
1
1
1
1
Options
Immunogen KLH conjugated synthetic peptide derived from human HSPC117/C22orf28
Isotype IgG
Purification Purified by Protein A.
Antigen
Alternative Name C22orf28 (C22orf28 Antibody Abstract)
Background

HSPC117, also known as C22orf28, is a 505 amino acid protein that is encoded by a gene which maps to human chromosome 22. A highly homologous protein identified in rodents, FAAP (focal adhesion associated protein), encoded by murine D10Wsu52e gene, has been suggested to play a role in regulating cell adhesion dynamics. Chromosome 22 houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

Synonyms: FAAP, Ankyrin repeat domain 54, C22orf28, Chromosome 22 open reading frame 28, DJ149A16.6, HSPC117, Hypothetical protein LOC51493, Novel protein HSPC117, RP1-149A16.6, RTCB_HUMAN, tRNA-splicing ligase RtcB homolog.

Gene ID 51493
Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months