Toxin of epsilon-zeta Postsegregational Killing System (ZETA) antibody (HRP)

Details for Product No. ABIN2835989
Target
Reactivity
Streptococcus agalactiae
8
Host
Rabbit
8
Clonality
Polyclonal
Conjugate
HRP
2
2
2
Application
ELISA, Western Blotting (WB)
8
4
Options
Immunogen Recombinant Streptococcus agalactiae Toxin zeta protein
Isotype IgG
Purification Caprylic Acid Ammonium Sulfate Precipitation
Target
Alternative Name Toxin zeta (ZETA Antibody Abstract)
Background Toxic component of a toxin-antitoxin (TA) module. Phosphorylates UDP-N-acetyl-D-glucosamine (UNAG) on the 3\'-hydroxyl group of the N-acetyl-D-glucosamine moiety, yielding UNAG-3P. UNAG-3P inhibits MurA, the first committed step in cell wall synthesis, which is then blocked. Phosphorylation is inhibited by cognate epsilon antitoxin. Part of a postsegregational killing (PSK) system involved in the killing of plasmid-free cells. The zeta toxin induces programmed cell death
Synonyms: UDP-N-acetylglucosamine kinase, UNAG kinase
UniProt P0A4M2
Application Notes Optimal working concentration should be determinde by the investigator.
Restrictions For Research Use only
Format Liquid
Buffer 0.03 % Proclin 300, 53 % Glycerol, 0.01 M PBS, pH 7.4
Preservative ProClin
Precaution of Use This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice Avoid repeated freeze.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Storage -20 °C/-80 °C
Storage Comment Upon delivery aliquot and store at -20 °C or -80 °C.