Toxin of epsilon-zeta Postsegregational Killing System (ZETA) (AA 1-287) antibody (HRP)

Catalog No. ABIN2835989

Product Details

Target: Toxin of epsilon-zeta Postsegregational Killing System (ZETA)

Binding Specificity: AA 1-287

Reactivity: Streptococcus agalactiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: ELISA

Cross-Reactivity: Streptococcus agalactiae

Purification: >95%, Protein G purified

Immunogen: Recombinant Streptococcus agalactiae Toxin zeta protein (1-287AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: Toxin of epsilon-zeta Postsegregational Killing System (ZETA)

Alternative Name: Toxin zeta (ZETA Products)

Synonyms: copy 2 antibody, zeta antibody

Background:

Background: Toxic component of a toxin-antitoxin (TA) module. Phosphorylates UDP-N-acetyl-D-glucosamine (UNAG) on the 3\'-hydroxyl group of the N-acetyl-D-glucosamine moiety, yielding UNAG-3P. UNAG-3P inhibits MurA, the first committed step in cell wall synthesis, which is then blocked. Phosphorylation is inhibited by cognate epsilon antitoxin. Part of a postsegregational killing (PSK) system involved in the killing of plasmid-free cells. The zeta toxin induces programmed cell death

Aliases: antibody, Toxin zeta antibody, UDP-N-acetylglucosamine kinase antibody, UNAG kinase antibody, EC 2.7.1.176 antibody

UniProt: P0A4M2