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Acyl-CoA Synthetase Long-Chain Family Member 6 (ACSL6) (AA 240-270), (Center) antibody Primary Antibody

ACSL6 Reactivity: Human, Mouse IHC (p), WB Host: Rabbit Polyclonal RB4703 unconjugated
Catalog No. ABIN2839301
$156.20
Plus shipping costs $45.00
80 μL ABIN2839301
80 μL ABIN2839301
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  • Target
    Acyl-CoA Synthetase Long-Chain Family Member 6 (ACSL6)
    Binding Specificity
    AA 240-270, Center
    • 10
    • 9
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Reactivity
    Human, Mouse
    • 41
    • 33
    • 13
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    Un-conjugated
    • 22
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    • 35
    • 22
    • 22
    • 5
    • 1
    • 1
    • 1
    • 1
    Specificity
    This FACL6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247~277 amino acids from the center region of human FACL6.
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This FACL6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-270 AA from the Central region of human FACL6.
    Clone
    RB4703
    Isotype
    Ig Fraction
  • Application Notes
    WB = 1:1000, IHC (p) = 1:50-100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    Acyl-CoA Synthetase Long-Chain Family Member 6 (ACSL6)
    Alternative Name
    FACL6 (ACSL6 Antibody Abstract)
    Synonyms
    ACS2, FACL6, LACS 6, LACS2, LACS5, ACSL6, MGC146229, Facl6, Lacsl, A330035H04Rik, AW050338, LACS, mKIAA0837, wu:fa04h02, wu:fc05h07, acyl-CoA synthetase long chain family member 6, acyl-CoA synthetase long-chain family member 6, ACSL6, acsl6, Acsl6, LOAG_15918, LOC416323
    Background
    FACL6 is involved in activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. It plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. FACL6 is expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derieved from fetal liver, haemopoietic stem cells from cord blood, bone marrow, and brain. Expression is low at earlier stages of erythroid development but is very high in reticulocytes. This protein is involved in myelodysplastic syndrome (MDS) with basophilia, acute myelogenous leukemia (AML) with eosinophilia, and acute eosinophilic leukemia (AEL). It is characterized by a chromosomal translocation t(5,12)(q31,p13) that involves ETV6 and ACSL6.
    Synonyms: Long-chain-fatty-acid--CoA ligase 6, Long-chain acyl-CoA synthetase 6, LACS 6
    Molecular Weight
    77680 DA
    Gene ID
    23305
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