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Haptoglobin antibody (HP) (Center) Primary Antibody

HP Reactivity: Human IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855722
$509.08
Plus shipping costs $45.00
100 μL
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  • Target See all Haptoglobin (HP) Antibodies
    Haptoglobin (HP)
    Binding Specificity
    • 17
    • 10
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 135
    • 45
    • 42
    • 17
    • 11
    • 10
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 132
    • 21
    • 17
    • 9
    • 7
    • 3
    Rabbit
    Clonality
    • 165
    • 22
    Polyclonal
    Conjugate
    • 100
    • 30
    • 13
    • 10
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Haptoglobin antibody is un-conjugated
    Application
    • 126
    • 82
    • 59
    • 27
    • 23
    • 22
    • 16
    • 15
    • 13
    • 11
    • 10
    • 9
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Characteristics
    Rabbit Polyclonal antibody to Haptoglobin (haptoglobin)
    Haptoglobin antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Haptoglobin. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000*
    Comment

    Positive Control: Target recombinant protein

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.59 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    Haptoglobin (HP)
    Alternative Name
    Haptoglobin (HP Products)
    Synonyms
    HP, wu:fb64e01, BP, HP2ALPHA2, HPA1S, HP-1, HPR, Zonulin, haptoglobin, haptoglobin-like, HP, hp, Hp, LOC479668, LOC101102413
    Background
    This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Secreted
    Molecular Weight
    45 kDa
    Gene ID
    3240
    Pathways
    Transition Metal Ion Homeostasis
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