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Haptoglobin antibody

HP Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855722
  • Target See all Haptoglobin (HP) Antibodies
    Haptoglobin (HP)
    Reactivity
    • 102
    • 44
    • 39
    • 14
    • 10
    • 10
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 116
    • 14
    • 10
    • 7
    • 7
    • 2
    Rabbit
    Clonality
    • 136
    • 19
    Polyclonal
    Conjugate
    • 81
    • 28
    • 11
    • 10
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Haptoglobin antibody is un-conjugated
    Application
    • 110
    • 62
    • 60
    • 21
    • 20
    • 18
    • 15
    • 14
    • 13
    • 13
    • 13
    • 12
    • 10
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human
    Characteristics
    Rabbit Polyclonal antibody to Haptoglobin (haptoglobin)
    Haptoglobin antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Haptoglobin. The exact sequence is proprietary.
    Isotype
    IgG
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    Discover our top product HP Primary Antibody
  • Application Notes
    WB: 1:5000-1:30000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    Haptoglobin (HP)
    Alternative Name
    haptoglobin (HP Products)
    Synonyms
    HP antibody, wu:fb64e01 antibody, BP antibody, HP2ALPHA2 antibody, HPA1S antibody, HP-1 antibody, HPR antibody, Zonulin antibody, haptoglobin antibody, haptoglobin-like antibody, HP antibody, hp antibody, Hp antibody, LOC479668 antibody, LOC101102413 antibody
    Background
    This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Secreted
    Molecular Weight
    45 kDa
    Gene ID
    3240
    UniProt
    P00738
    Pathways
    Transition Metal Ion Homeostasis
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