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NK2 Homeobox 5 antibody

NKX2-5 Reactivity: Human WB, IF, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856166
  • Target See all NK2 Homeobox 5 (NKX2-5) Antibodies
    NK2 Homeobox 5 (NKX2-5)
    Reactivity
    • 40
    • 20
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 42
    • 7
    • 1
    Rabbit
    Clonality
    • 44
    • 6
    Polyclonal
    Conjugate
    • 36
    • 4
    • 3
    • 3
    • 2
    • 2
    This NK2 Homeobox 5 antibody is un-conjugated
    Application
    • 43
    • 30
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Rabbit Polyclonal antibody to Nkx2.5 (NK2 transcription factor related, locus 5 (Drosophila))
    Nkx2.5 antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Nkx2.5. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product NKX2-5 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Validation: Comparison

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.21 mg/mL
    Buffer
    1XPBS, 20 % Glycerol ( pH 7), 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    NK2 Homeobox 5 (NKX2-5)
    Alternative Name
    NK2 homeobox 5 (NKX2-5 Products)
    Synonyms
    CHNG5 antibody, CSX antibody, CSX1 antibody, HLHS2 antibody, NKX2.5 antibody, NKX2E antibody, NKX4-1 antibody, VSD3 antibody, Csx antibody, Nkx-2.5 antibody, Nkx2.5 antibody, tinman antibody, nk2.5 antibody, nkx2-5 antibody, zgc:111912 antibody, AR2 antibody, XNkx2-5 antibody, csx antibody, nkx-2.5 antibody, nkx2-5b antibody, nkx2.5 antibody, NKX2-5 antibody, Nkx2-5 antibody, csx1 antibody, nkx2e antibody, XNkx-2.5 antibody, CNKX-2.5 antibody, NKX-2.5 antibody, NK2 homeobox 5 antibody, NK2 homeobox 5 S homeolog antibody, NKX2-5 antibody, Nkx2-5 antibody, nkx2.5 antibody, nkx2-5.S antibody, nkx2-5 antibody
    Background
    Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development (Shiojima et al., 1995 [PubMed 7665173]). It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.[supplied by OMIM]

    Cellular Localization: Nucleus
    Molecular Weight
    35 kDa
    Gene ID
    1482
    UniProt
    P52952
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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