ABCC4 antibody (AA 495-705)

Catalog No. ABIN3023193

Product Details anti-ABCC4 Antibody

Target: ABCC4 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4))

Binding Specificity: AA 495-705

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: FGKKYEKERY EKVIKACALK KDLQLLEDGD LTVIGDRGTT LSGGQKARVN LARAVYQDAD IYLLDDPLSA VDAEVSRHLF ELCICQILHE KITILVTHQL QYLKAASQIL ILKDGKMVQK GTYTEFLKSG IDFGSLLKKD NEESEQPPVP GTPTLRNRTF SESSVWSQQS SRPSLKDGAL ESQDTENVPV TLSEENRSEG KVGFQAYKNY F

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 495-705 of human MRP4/ABCC4 (NP_001098985.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ABCC4

Target: ABCC4 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4))

Alternative Name: ABCC4 (ABCC4 Products)

Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants.,ABCC4,MOAT-B,MOATB,MRP4,Cancer,Drug resistance,MRP-related proteins,Signal Transduction,Endocrine & Metabolism,Stem Cells,ABCC4

Molecular Weight: 88 kDa/96 kDa/144 kDa/149 kDa

Gene ID: 10257

UniProt: O15439