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CD40 antibody (CD40 Molecule, TNF Receptor Superfamily Member 5) (AA 1-360) Primary Antibody

CD40 Reactivity: Human, Rat IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3030398
$493.63
Plus shipping costs $45.00
100 μg
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  • Target
    CD40
    Binding Specificity
    AA 1-360
    • 21
    • 20
    • 17
    • 15
    • 13
    • 12
    • 11
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Reactivity
    Human, Rat
    • 238
    • 114
    • 44
    • 13
    • 9
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Host
    Rabbit
    • 154
    • 112
    • 50
    • 5
    • 1
    • 1
    Clonality
    Polyclonal
    • 209
    • 111
    • 1
    Conjugate
    This CD40 antibody is un-conjugated
    • 154
    • 30
    • 29
    • 22
    • 13
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    • 188
    • 106
    • 78
    • 64
    • 48
    • 37
    • 27
    • 21
    • 21
    • 13
    • 12
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Purification
    Antigen affinity
    Immunogen
    Human partial recombinant protein (AA 1-360) was used as the immunogen for this p50 antibody.
    Isotype
    IgG
  • Application Notes
    Titration of the p50 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    The p50 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeat freeze/thaws.
  • Target
    CD40
    Alternative Name
    p50 (CD40 Antibody Abstract)
    Synonyms
    Bp50, CDW40, TNFRSF5, p50, AI326936, GP39, HIGM1, IGM, IMD3, T-BAM, TRAP, Tnfrsf5, TNFSF5, CD40 molecule, CD40 antigen, CD40, Cd40
    Background
    Nuclear factor NF-kappa-B p105/p50, also called EBP-1 is a protein that in humans is encoded by the NFKB1 gene. By fluorescence in situ hybridization, the gene was assigned to human chromosome 4q24. NFKB1 is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NFKB1 proteins by p105 and generation of p50 by a cotranslational processing.
    Gene ID
    4790
    Pathways
    NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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