SLC1A1 antibody (N-Term)

Catalog No. ABIN3042859

Product Details anti-SLC1A1 Antibody

Target: SLC1A1 (Solute Carrier Family 1 (Neuronal/epithelial High Affinity Glutamate Transporter, System Xag), Member 1 (SLC1A1))

Binding Specificity: AA 10-27, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC1A1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Excitatory amino acid transporter 3(SLC1A1) detection. Tested with WB in Human.

Sequence: EWKRFLKNNW VLLSTVAA

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Excitatory amino acid transporter 3(SLC1A1) detection. Tested with WB in Human.
Gene Name: solute carrier family 1(neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
Protein Name: Excitatory amino acid transporter 3

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human EAAT3(10-27aa EWKRFLKNNWVLLSTVAA).

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SLC1A1

Target: SLC1A1 (Solute Carrier Family 1 (Neuronal/epithelial High Affinity Glutamate Transporter, System Xag), Member 1 (SLC1A1))

Alternative Name: SLC1A1 (SLC1A1 Products)

Background: Solute carrier family 1 member 1, also called SLC1A1, is a protein that in humans is encoded by the SLC1A1 gene. By Southern analysis of a panel of human/rodent somatic cell hybrids and by fluorescence in situ hybridization(FISH), this gene is mapped to 9p24.2. This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are though to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect.

Synonyms: EAA3_HUMAN antibody|EAAC 1 antibody|EAAC1 antibody|EAAT 3 antibody|Excitatory amino acid carrier 1 antibody|Excitatory amino acid carrier1 antibody|Excitatory amino acid transporter 3 antibody|Excitatory amino acid transporter3 antibody|Excitatory amino-acid carrier 1 antibody|GLUTAMATE TRANSPORTER, HIGH-AFFINITY antibody|MEAAC 1 antibody|MEAAC1 antibody|Neuronal and epithelial glutamate transporter antibody|REAAC 1 antibody|REAAC1 antibody|Slc1 a1 antibody|Slc1a 1 antibody|SLC1A1 antibody|Sodium dependent glutamate/aspartate transporter 3 antibody|Sodium-dependent glutamate/aspartate transporter 3 antibody|Solute carrier family 1(neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 antibody|SOLUTE CARRIER FAMILY 1(NEURONAL/EPITHELIAL HIGH AFFINITY GLUTAMATE TRANSPORTER), MEMBER 1 antibody|Solute carrier family 1(neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 antibody|Solute carrier family 1 member 1 antibody|Solute carrier family 1, member 1 antibody

UniProt: P43005

Pathways: Dicarboxylic Acid Transport