CCR4 antibody (Middle Region)

Catalog No. ABIN3043172

Product Details anti-CCR4 Antibody

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Binding Specificity: AA 346-360, Middle Region

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR4 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for C-C chemokine receptor type 4(CCR4) detection. Tested with WB in Mouse,Rat.

Sequence: SYTQSTVDHD FRDAL

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for C-C chemokine receptor type 4(CCR4) detection. Tested with WB in Mouse,Rat.
Gene Name: chemokine(C-C motif) receptor 4
Protein Name: C-C chemokine receptor type 4(C-C CKR-4/CC-CKR-4/CCR-4/CCR4)

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of mouse CCR4(346-360aa, SYTQSTVDHDFRDAL), identical to the related rat sequence.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

References for anti-CCR4 antibody (ABIN3043172)

Zhao, Bu, Wang, Ma, Ma: "GEC-derived SFRP5 inhibits Wnt5a-induced macrophage chemotaxis and activation." in: PLoS ONE, Vol. 9, Issue 1, pp. e85058, (2014) (PubMed).

Target Details for CCR4

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Alternative Name: CCR4 (CCR4 Products)

Background: CCR4,C-C chemokine receptor type 4 is a protein that in humans is encoded by the CCR4 gene. CCR4 has also recently been designated CD194(cluster of differentiation 194). The protein encoded by this gene belongs to the G protein-coupled receptor family. It is a receptor for the following CC chemokines. The CCR4 gene is mapped to chromosome 3. Chemokines are a group of small structurally related proteins that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

Synonyms: C C chemokine receptor type 4 antibody|C C CKR 4 antibody|C-C chemokine receptor type 4 antibody|C-C CKR-4 antibody|CC CKR 4 antibody|CC-CKR-4 antibody|CCR 4 antibody|CCR-4 antibody|CCR4 antibody|CCR4_HUMAN antibody|CD194 antibody|Chemokine(CC motif) receptor 4 antibody|chemokine C C motif receptor 4 antibody|ChemR13 antibody|CKR4 antibody|CMKBR 4 antibody|CMKBR4 antibody|HGCN 14099 antibody|K5 5 antibody|K5-5 antibody|MGC88293 antibody

UniProt: P51680