TAS2R4 antibody

Catalog No. ABIN350977

Product Details anti-TAS2R4 Antibody

Target: TAS2R4 (Tas2r108) (Taste Receptor, Type 2, Member 4 (Tas2r108))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAS2R4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Specific for TAS2R4.

Cross-Reactivity: Human, Marmoset

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from human TAS2R4 conjugated to blue carrier protein was used as the antigen.

Isotype: IgG

Application Details

Application Notes: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for TAS2R4

Target: TAS2R4 (Tas2r108) (Taste Receptor, Type 2, Member 4 (Tas2r108))

Alternative Name: TAS2R4 (Tas2r108 Products)

Synonyms: T2R4 antibody, taste 2 receptor member 4 antibody, TAS2R4 antibody

Background: This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. FUNCTION: Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. SUBCELLULAR LOCATION: Membrane, Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. MISCELLANEOUS: Several bitter taste receptors are expressed in a single taste receptor cell.<||a href="http://www.enzim.hu/hmmtop1.1/server/submit.html"><||/a>,Human Taste R,Taste receptor type 2 member 4, T2R4

UniProt: Q9NYW5