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Gelsolin antibody (GSN) (Internal Region) Primary Antibody

GSN Reactivity: Human, Mouse, Rat, Dog WB Host: Goat Polyclonal unconjugated
Catalog No. ABIN374752
$537.90
Plus shipping costs $45.00
0.1 mg
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Available
  • Target
    Gelsolin (GSN)
    Binding Specificity
    • 16
    • 12
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 110
    • 33
    • 32
    • 10
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog
    Host
    • 78
    • 27
    • 14
    • 1
    Goat
    Clonality
    • 78
    • 42
    Polyclonal
    Conjugate
    • 57
    • 14
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Gelsolin antibody is un-conjugated
    Application
    • 84
    • 41
    • 35
    • 30
    • 26
    • 22
    • 16
    • 14
    • 13
    • 6
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB)
    Specificity
    This antibody reacts to Gelsolin.
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Rat, Canine.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Immunogen
    Peptide with sequence C-PRLKDKKMDAHP, from the internal region of the protein sequence
  • Application Notes
    Peptide ELISA: 1/128000. Western Blot: 0.1 - 0.3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Gelsolin (GSN)
    Alternative Name
    Gelsolin (GSN Antibody Abstract)
    Synonyms
    ADF, AGEL, CG1106, DGS, Dmel\\CG1106, gel, scin, cb107, gsn, sb:cb107, u-gelsolin, wu:fi16f06, gelsolin, Gelsolin, gelsolin S homeolog, gelsolin a, GSN, Gel, Gsn, gsn.S, gsn, gsna
    Background
    Gelsolin is a calcium dependent actin binding protein. It is a potent modulator of actin filament length and gelation. Gelsolin has been shown to exist in at least two variant forms, cytoplasmic gelsolin and plasma gelsolin. Plasma gelsolin has also been called actin depolymerizing factor (ADF) or brevin. Human plasma and rabbit macrophage gelsolins differ by the presence of a 25 amino acid residue extension at the NH2 terminus in the human plasma gelsolin, which appears to account for the difference in relative molecular weights.Synonyms: AGEL, Actin-depolymerizing factor, Brevin, GSN
    Gene ID
    2934
    NCBI Accession
    NP_000168
    UniProt
    P06396
    Pathways
    Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy
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