BCL10 antibody (B-Cell CLL/lymphoma 10) (AA 122-168)

Details for Product anti-BCL10 Antibody No. ABIN379257
Antigen
  • CARMEN
  • CIPER
  • CLAP
  • c-E10
  • mE10
  • BCL10
  • AI132454
  • BCL-10
  • C81403
  • ME10
  • cE10
  • bcl10
  • B-cell CLL/lymphoma 10
  • B-cell lymphoma/leukemia 10-like
  • B cell leukemia/lymphoma 10
  • B-cell lymphoma/leukemia 10
  • BCL10
  • Bcl10
  • bcl10
  • LOC100223183
Epitope
AA 122-168
47
23
12
12
8
8
8
5
4
3
3
2
2
2
1
1
1
1
Reactivity
Human
271
83
66
2
2
1
1
1
1
1
1
1
Host
Mouse
147
125
1
Clonality (Clone)
Monoclonal ()
Conjugate
This BCL10 antibody is un-conjugated
10
8
7
6
5
4
4
4
4
4
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
214
106
89
82
76
52
21
17
15
13
8
6
3
2
1
1
1
Options
Immunogen Human recombinant Bcl-10.
Clone 151
Isotype IgG1
Specificity Monoclonal Anti-Bcl-10 reacts specifically with human Bcl-10. The epitope recognized by the antibody resides within amino acids 122-168 of human Bcl-10 Molecule. Bcl-10, also designated as CIPER, mE10, cE10, CARMEN, and CLAP, is an N-terminal CARD (Caspase Recruitment Domain) containing protein. It is a cellular homologue of the equine herpesvirus-2 protein E-10 (vCLAP). Bcl-10 was implicated in the regulation of apoptosis by interacting with caspase 9, enhancing procaspase 9 processing, and triggering its activation when overexpressed in the cell. Bcl-10 cellular overexpression induces JNK, p38, and NF-kB activation. Deregulation of Bcl-10 expression is also demonstrated to be involved in cellular oncogenesis.
Purification Protein G purified
Plasmids, Primers & others Plasmids, Primers & others BCL10 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name BCL10 / BCL-10 (BCL10 Antibody Abstract)
Background Name/Gene ID: BCL10
Family: Apoptosis

Synonyms: BCL10, Bcl-10, B-cell CLL/lymphoma 10, B-cell lymphoma/leukemia 10, CARMEN, CARD-like apoptotic protein, CCARMEN, C-E10, CIPER, Cellular-E10, HCLAP, Cellular homolog of vCARMEN, CLAP, ME10
Gene ID 8915
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity
Comment

Target Species of Antibody: Human

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Buffer contains: 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze.
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