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TACI antibody

TNFRSF13B Reactivity: Human FACS Host: Rat Monoclonal 1A1 unconjugated
Catalog No. ABIN4888498
  • Target See all TACI (TNFRSF13B) Antibodies
    TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))
    Reactivity
    • 29
    • 25
    • 6
    • 2
    • 2
    • 2
    • 2
    Human
    Host
    • 31
    • 8
    • 8
    • 5
    Rat
    Clonality
    • 36
    • 16
    Monoclonal
    Conjugate
    • 28
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TACI antibody is un-conjugated
    Application
    • 40
    • 19
    • 14
    • 14
    • 13
    • 7
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Flow Cytometry (FACS)
    Specificity
    The rat monoclonal antibody 1A1 recognizes an extracellular epitope of CD267 / TACI, a 32 kDa type III transmembrane protein expressed by B cells and possibly by some activated T cells.
    Cross-Reactivity (Details)
    Human
    Purification
    Purified by protein-G affinity chromatography.
    Purity
    > 95 % (by SDS-PAGE)
    Immunogen
    CD267-transfected RBL cells
    Clone
    1A1
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product TNFRSF13B Primary Antibody
  • Application Notes
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Target
    TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))
    Alternative Name
    CD267 / TACI (TNFRSF13B Products)
    Background
    TNF receptor superfamily member 13B,CD267 / TACI (transmembrane activator calcium modulator and cyclophilin ligand interactor), a TNFR superfamily transmembrane protein, is expressed on B cells (predominantly on CD27+ memory cells), multiple myeloma cells and B cell chronic lymphocytic leukemia (B-CLL). Its triggering leads to activation of the transcription factors NFAT, AP1, and NF-kappa-B. It plays a crucial role in humoral immunity. Mutations in CD267 are associated with common variable immunodeficiency and IgA deficiency.,RYZN, TACI, CVID2, IGAD2, TNFRSF14B
    Gene ID
    23495
    UniProt
    O14836
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