L3MBTL2 antibody (L(3)mbt-Like 2 (Drosophila)) (AA 1-230)

Details for Product anti-L3MBTL2 Antibody No. ABIN4889662, Supplier: Log in to see
Antigen
  • L3MBTL2
  • im:7137244
  • wu:fb04e09
  • zgc:66491
  • H-l(3)mbt-l
  • L3MBT
  • 4732493N06Rik
  • M4mbt
  • L3MBTL2 polycomb repressive complex 1 subunit
  • L3MBTL2, polycomb repressive complex 1 subunit
  • l(3)mbt-like 2 (Drosophila)
  • L3MBTL2
  • l3mbtl2
  • L3mbtl2
Epitope
AA 1-230
13
10
7
4
3
2
2
2
2
2
1
1
1
Reactivity
Human
54
12
10
9
7
5
3
3
3
2
1
Host
Rabbit
47
8
Clonality
Polyclonal
Conjugate
This L3MBTL2 antibody is un-conjugated
4
3
3
2
2
2
Application
Western Blotting (WB)
48
28
7
5
5
1
1
1
Options
Supplier
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Immunogen This L3MBTL2 antibody was raised against a His-tagged fusion protein containing amino acids 1-230 of human L3MBTL2.
Purification None
Plasmids, Primers & others Plasmids, Primers & others L3MBTL2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name L3MBTL2 (L3MBTL2 Antibody Abstract)
Background L3MBTL2 (Lethal (3) malignant brain tumor-like 2 protein) is a putative member of the polycomb group family and is the human homolog of Drosophila Sfmbt, critical for Hox gene silencing. L3MBTL2 contains one FCS-type zinc finger and four MBT (malignant brain tumor) repeats. L3MBTL2 associates with chromatin-remodeling complexes and helps inhibit the expression of proteins that trigger the cells into mitosis. L3MBTL2 is a part of a complex involved in the G0 phase of the cell cycle. This complex contains other proteins such as E2F-6, Max or HP1 gamma, and participates in transcriptional repression.
Molecular Weight 90 kDa
Gene ID 83746
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage -20 °C
Storage Comment Antibodies in solution can be stored at -20 °C for 2 years.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-L(3)mbt-Like 2 (Drosophila) (L3MBTL2) (AA 1-230) antibody (ABIN4889662) L3MBTL2 pAb tested by Western blot. Detection of L3MBTL2 by Western blot analysis wit...
Product cited in: LaFave, Béguelin, Koche, Teater, Spitzer, Chramiec, Papalexi, Keller, Hricik, Konstantinoff, Micol, Durham, Knutson, Campbell, Blum, Shi, Doud, Krivtsov, Chung, Khodos, de Stanchina, Ouerfelli et al.: "Loss of BAP1 function leads to EZH2-dependent transformation. ..." in: Nature medicine, Vol. 21, Issue 11, pp. 1344-9, 2015 (PubMed).

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