L3MBTL2 antibody (C-Term)

Catalog No. ABIN2778379

Cited in 1 publication. The Rabbit Polyclonal anti-L3MBTL2 antibody (ABIN2778379) specifically detects L3MBTL2 in WB. The antibody is reactive with Human, Dog, Cow, Horse and Pig samples.

Quick Overview for L3MBTL2 antibody (C-Term) (ABIN2778379)

Target: L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

Reactivity: Human, Dog, Cow, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This L3MBTL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-L3MBTL2 Antibody

Binding Specificity: C-Term

Purpose: L3MBTL2 Antibody - C-terminal region

Sequence: LLEDDPQGAR KISSEPVPGE IIAVRVKEEH LDVASPDKAS SPELPVSVEN

Predicted Reactivity: Cow: 85%, Dog: 85%, Horse: 85%, Human: 100%, Pig: 92%

Characteristics: This is a rabbit polyclonal antibody against L3MBTL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human L3MBTL2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104225

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-L3MBTL2 antibody (ABIN2778379)

Collins, Wright, Edwards, Davis, Grinham, Cole, Goward, Aguado, Mallya, Mokrab, Huckle, Beare, Dunham: "A genome annotation-driven approach to cloning the human ORFeome." in: Genome biology, Vol. 5, Issue 10, pp. R84, (2004) (PubMed).

Target Details for L3MBTL2

Target: L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

Alternative Name: L3MBTL2

Background:

Background Information: L3MBTL2 contains 1 FCS-type zinc finger and 4 MBT repeats. It is putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis.

Gene Name: L(3)mbt-like 2 (Drosophila)

Alternative Symbols: L3MBT, H-l(3)mbt-l

Protein Name: Lethal(3)malignant brain tumor-like protein 2

Molecular Weight: 79kDa

Gene ID: 83746

NCBI Accession: NP_113676

UniProt: Q969R5