HMGB2 antibody (AA 92-118)
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- Target See all HMGB2 Antibodies
- HMGB2 (High Mobility Group Box 2 (HMGB2))
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Binding Specificity
- AA 92-118
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HMGB2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Cross-Reactivity (Details)
- Expected species reactivity: Rat, Bovine, Pig
- Purification
- Purified
- Immunogen
- A portion of amino acids 92-118 from the human protein was used as the immunogen for this HMGB2 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product HMGB2 Primary Antibody
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- Application Notes
- Titration of the HMGB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the HMGB2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- HMGB2 (High Mobility Group Box 2 (HMGB2))
- Alternative Name
- HMGB2 (HMGB2 Products)
- Background
- HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
- UniProt
- P26583
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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