GAP43 antibody (Growth Associated Protein 43) Primary Antibody
- Human, Mouse, Rat
- This GAP43 antibody is un-conjugated
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- This antibody detects endogenous levels of GAP43 protein. (region surrounding Ala35)
- Cross-Reactivity (Details)
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
- Affinity chromatography
- > 95 % by SDS-PAGE
anti-Growth Associated Protein 43 (GAP43) (AA 9-100) antibody Primary Antibody
GAP43 Reactivity: Human, Mouse, Rat ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugatedanti-Growth Associated Protein 43 (GAP43) (N-Term) antibody Primary Antibody
GAP43 Reactivity: Human, Mouse, Rat, Chicken, Cow, Monkey, Zebrafish (Danio rerio) IC, IF, IHC, WB Host: Rabbit Polyclonal unconjugated
- Application Notes
Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
- For Research Use only
- 1,0 mg/mL
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
- Alternative Name
- GAP43 (GAP43 Antibody Abstract)
- B-50, PP46, Basp2, GAP-43, b-50, gap-43, gap43b, pp46, cb310, gap, gap43, gap43a, growth associated protein 43, growth associated protein 43 L homeolog, growth associated protein 43 S homeolog, GAP43, Gap43, gap43.L, gap43, gap43.S
- GAP-43 (growth associated protein 43, B-50, PP46, calmodulin-binding protein P-57, neuromodulin, neuron growth-associated protein 43, protein F1) is a crucial component for regenerative response in the nervous system that is present at high levels in neuronal growth cones during development and axonal regeneration. GAP-43 is normally produced by neurons during developmental growth and axonal regeneration, but it is also expressed in specific regions of the normal adult nervous system. The neuron-specific ELAV/Hu family member, HuD, interacts with and stabilizes GAP-43 mRNA in developing neurons and leads to increased levels of GAP-43 protein. Heterozygous GAP-43 knockout mice with GAP-43 levels reduced by one-half display significant memory impairments in cued conditioning or on tests of nociceptive or auditory perception.Synonyms: Axonal membrane protein GAP-43, Growth-associated protein 43, Neural phosphoprotein B-50, Neuromodulin, PP46
- Molecular Weight
- approx. 38, 43 kDa
- Gene ID
- NCBI Accession