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FOLR1 antibody (Folate Receptor 1 (Adult)) Primary Antibody

FOLR1 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499072
$513.70
Plus shipping costs $45.00
0.1 mg
local_shipping Shipping to: United States
Available
  • Target
    FOLR1
    Reactivity
    • 55
    • 21
    • 17
    • 14
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 53
    • 16
    • 9
    • 1
    Rabbit
    Clonality
    • 65
    • 14
    Polyclonal
    Conjugate
    • 49
    • 8
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FOLR1 antibody is un-conjugated
    Application
    • 56
    • 44
    • 30
    • 23
    • 14
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    This antibody detects endogenous levels of FR-α (Y80) protein. (region surrounding Tyr80)
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography using epitope-specific immunogen
    Purity
    > 95 % (by SDS-PAGE)
  • Application Notes
    Western blot: 1: 500 - 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    FOLR1
    Alternative Name
    Folate Receptor alpha (FOLR1 Antibody Abstract)
    Synonyms
    FBP, FOLR, fbp, folr, folr1, FBP1, Folbp-1, Folbp1, Fbp1, FOLR1, Folr1, folate receptor 1, folate receptor 1 (adult), folate receptor 1 (adult) L homeolog, zgc:165502, Folate receptor alpha, folate receptor alpha, FOLR1, folr1, folr1.L, zgc:165502, Folr1, LOC100066084, LOC100725439
    Background
    Folate is an essential vitamin that must be obtained from food intake through intestinal absorption in mammals. Folate and reduced folic acid derivatives bind to the folate receptor (FR) family, which mediates the endocytosis of 5-methyltetrahydrofolate into the cell. The folate receptors consist of five members, α, β, γ, γ' (which is produced by alternative splicing) and δ. β-FR is attached to the membrane by a GPI anchor and is expressed in malignant tissues of epithelial and nonepithelial origin. γ-FR is expressed in tissues of hematopoietic origin, such as spleen, thymus and bone marrow. The expression pattern of δ-FR is elusive, which suggests that it is highly restricted both spatially and temporally. The α isoform of the folate receptor is used as a highly selective tumor marker and may be targeted for the delivery of therapeutic compounds to tumor cells by coupling to derivatives of folic acid.Synonyms: Adult folate-binding protein, FOLR, FOLR1, FR-alpha, Folate receptor 1, KB cells FBP, MOv18, Ovarian tumor-associated antigen MOv18
    Molecular Weight
    approx. 34 kDa
    Gene ID
    2348
    NCBI Accession
    NP_000793
    UniProt
    P15328
    Pathways
    Dicarboxylic Acid Transport
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