Pseudouridylate Synthase 10 (PUS10) antibody (Alexa Fluor 750)

Details for Product No. ABIN4999209
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
45
27
18
2
2
2
2
2
2
1
1
1
1
1
Host
Rabbit
45
Clonality
Polyclonal
Conjugate
Alexa Fluor 750
4
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
29
19
12
5
3
1
Options
Immunogen KLH conjugated synthetic peptide derived from human PUS10/CCDC139
Isotype IgG
Purification Purified by Protein A.
Antigen
Alternative Name CCDC139 (PUS10 Antibody Abstract)
Background

Pseudouridination is the isomerization of uridine to pseudouridine. It is the most common posttranscriptional nucleotide modification found in RNA. It is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones which facilitate the correct folding and assembly of tRNAs.

Synonyms: CCDC139, Coiled coil domain containing protein 139, DOBI, FLJ32312, MGC126729, Putative tRNA pseudouridine synthase Pus10, tRNA pseudouridine 55 synthase, tRNA uridine isomerase, PUS10_HUMAN.

Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months