PUS10 antibody (AA 290-529)

Catalog No. ABIN7269738

The Rabbit Polyclonal anti-PUS10 antibody (ABIN7269738) specifically detects PUS10 in WB. The antibody is reactive with Human samples.

Quick Overview for PUS10 antibody (AA 290-529) (ABIN7269738)

Target: PUS10 (Pseudouridylate Synthase 10 (PUS10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUS10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PUS10 Antibody

Binding Specificity: AA 290-529

Purpose: PUS10 Rabbit pAb

Sequence: VAGRYNKYSR NLPQTPWIID GERKLESSVE ELISDHLLAV FKAESFNFSS SGREDVDVRT LGNGRPFAIE LVNPHRVHFT SQEIKELQQK INNSSNKIQV RDLQLVTREA IGHMKEGEEE KTKTYSALIW TNKAIQKKDI EFLNDIKDLK IDQKTPLRVL HRRPLAVRAR VIHFMETQYV DEHHFRLHLK TQAGTYIKEF VHGDFGRTKP NIGSLMNVTA DILELDVESV DVDWPPALDD

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 290-529 of human PUS10 (NP_653310.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PUS10

Target: PUS10 (Pseudouridylate Synthase 10 (PUS10))

Alternative Name: PUS10

Background: Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).,PUS10,CCDC139,DOBI,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Caspases,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial translation,PUS10

Molecular Weight: 60kDa

Gene ID: 150962

UniProt: Q3MIT2