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HCP5 antibody (AA 1-80) (AbBy Fluor® 750)

HCP5 Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 750
Catalog No. ABIN5004328
  • Target See all HCP5 products
    HCP5 (HLA Complex P5 (Non-Protein Coding) (HCP5))
    Binding Specificity
    • 14
    • 5
    • 3
    • 2
    AA 1-80
    Reactivity
    Human
    Host
    • 21
    • 3
    Rabbit
    Clonality
    • 23
    • 1
    Polyclonal
    Conjugate
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HCP5 antibody is conjugated to AbBy Fluor® 750
    Application
    • 18
    • 12
    • 12
    • 9
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HCP5
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    HCP5 (HLA Complex P5 (Non-Protein Coding) (HCP5))
    Alternative Name
    HCP5 (HCP5 Products)
    Synonyms
    6S2650E antibody, D6S2650E antibody, P5-1 antibody, HLA complex P5 (non-protein coding) antibody, HCP5 antibody
    Background

    Synonyms: HLA class I histocompatibility antigen protein P5, HLA complex protein P5, Protein P5 1, HCP5_HUMAN.

    Background: HCP5 is a region present on chromosome 6p21.3 that is characterized by multiple duplicated gene families. HCP5 (HLA class I histocompatibility antigen protein P5), also known as P5-1, is a 132 amino acid protein that is encoded by a gene mapping to human chromosome 6p21.33. Localizing within the MHC class I region, HCP5 is not structurally related to other MHC class I genes, but does have high sequence similarity with HERV-L and HERV-16. HCP5 also has high sequence homology to retroviral Pol genes, making it a possible candidate for interaction with HIV-1 through an antisense mechanism that prevents retrovirus transcription. Single-nucleotide polymorphisms (SNPs) to the region of the HCP5 gene that corresponds with HLA-B has been linked to a lower HIV-1 viral set point. HCP5 is highly expressed in lymphoid tissues, spleen and activated lymphocytes, as well as B-cell and natural killer (NK) cell lines.

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