Kv2.1/KCNB1 antibody (C-Term)

Catalog No. ABIN5515521

Product Details anti-Kv2.1/KCNB1 Antibody

Target: Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Horse, Cow, Dog, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kv2.1/KCNB1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MAKTQSQPIL NTKESAAQSK PKEELEMESI PSPVAPLPTR TEGVIDMRSM

Predicted Reactivity: Cow: 93%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 85%, Pig: 93%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against KCNB1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human KCNB1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Kv2.1/KCNB1

Target: Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))

Alternative Name: KCNB1 (KCNB1 Products)

Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members.

Alias Symbols: KCNB1,

Protein Interaction Partner: STX1A, KCNG3, KCNG4, KCNV1, KCNB2, KCNG1, KCNB1, SRC, SUMO1, NEDD4L, KCNV2, KCNG2, KCNS3, PTPRE, SNAP25, KCNH1,

Protein Size: 858

Gene ID: 3745

NCBI Accession: NP_004966

UniProt: Q14721

Pathways: Synaptic Membrane