C1GALT1-Specific Chaperone 1 (C1GALT1C1) (N-Term) antibody

Details for Product No. ABIN5516325
Target
Binding Specificity
N-Term
2
2
1
Reactivity
Human
17
5
4
1
1
1
1
1
Host
Rabbit
15
2
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
1
Application
Western Blotting (WB)
11
6
5
1
1
Options
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human C1GALT1C1
Sequence GNRMHHHEHH HLQAPNKEDI LKISEDERME LSKSFRVYCI ILVKPKDVSL
Purification Affinity purified
Target
Alternative Name C1GALT1C1 (C1GALT1C1 Antibody Abstract)
Background This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.

Alias Symbols: TNPS, COSMC, MST143, C1GALT2, HSPC067, C38H2-L1

Protein Size: 375
Gene ID 29071
NCBI Accession NM_001011551, NP_001011551
UniProt Q96EU7
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.