PCDHA7 antibody (Protocadherin alpha 7) (AA 272-300)

Details for Product anti-PCDHA7 Antibody No. ABIN5532666
Antigen
Epitope
AA 272-300
8
8
7
7
4
1
1
Reactivity
Human
23
Host
Rabbit
17
6
Clonality
Polyclonal
Conjugate
This PCDHA7 antibody is un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
23
20
16
2
1
Options
Immunogen This PCDHA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-300 amino acids from the Central region of human PCDHA7.
Isotype Ig Fraction
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Antigen
Alternative Name PCDHA7 (PCDHA7 Antibody Abstract)
Background This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Molecular Weight 101 kDa
Gene ID 56141
UniProt Q9UN72
Application Notes For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Supplier Images
Image no. 1 for anti-Protocadherin alpha 7 (PCDHA7) (AA 272-300) antibody (ABIN5532666) Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Image no. 2 for anti-Protocadherin alpha 7 (PCDHA7) (AA 272-300) antibody (ABIN5532666) PCDHA7 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded...