PCDHA7 antibody (Protocadherin alpha 7) (AA 279-308)

Details for Product anti-PCDHA7 Antibody No. ABIN954035
Antigen
Epitope
AA 279-308, Middle Region
9
7
7
7
4
1
Reactivity
Human
23
Host
Rabbit
17
6
Clonality
Polyclonal
Conjugate
This PCDHA7 antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
23
20
16
2
Options
Immunogen Synthetic peptide - KLH conjugated - corresponding to the central region (between 279-308 aa) of human PCDHA7.
Isotype Ig Fraction
Specificity This antibody detecs human PCDHA7 (Center).
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Purified through a protein A column, followed by peptide affinity purification.
Antigen
Alternative Name PCDHA7 (PCDHA7 Antibody Abstract)
Background The PCDHA7 gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.Synonyms: CNRS4, PCDH-alpha-7, Protocadherin alpha-7
Gene ID 56141
NCBI Accession NP_061733
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Image no. 1 for anti-Protocadherin alpha 7 (PCDHA7) (AA 279-308), (Middle Region) antibody (ABIN954035) Immunohistochemistry analysis in formalin-fixed, paraffin-embedded human brain tissue...
Image no. 2 for anti-Protocadherin alpha 7 (PCDHA7) (AA 279-308), (Middle Region) antibody (ABIN954035) Western blot analysis in NCI-H292 cell line lysates (35ug/lane) using PCDHA7 Antibody...