TRADD antibody (TNFRSF1A-Associated Via Death Domain) (AA 126-151)

Details for Product anti-TRADD Antibody No. ABIN5534758
Antigen
Epitope
AA 126-151
12
9
8
8
8
7
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
94
38
25
7
5
2
2
2
Host
Rabbit
93
5
Clonality
Polyclonal
Conjugate
This TRADD antibody is un-conjugated
4
3
3
2
2
2
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
89
54
42
24
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21
12
11
4
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1
1
Options
Immunogen This TRADD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-151 amino acids from the Central region of human TRADD.
Isotype Ig Fraction
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Antigen
Alternative Name TRADD (TRADD Antibody Abstract)
Background The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq].
Molecular Weight 34 kDa
Gene ID 8717
UniProt Q15628
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C
Application Notes For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

For IF starting dilution is: 1:10~50
Restrictions For Research Use only
Format Liquid
Concentration 0.36 mg/mL
Buffer Supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Supplier Images
Image no. 1 for anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 126-151) antibody (ABIN5534758) Flow cytometric analysis of Hela cells (right histogram) compared to a negative contr...
Image no. 2 for anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 126-151) antibody (ABIN5534758) Western blot analysis in Hela cell line lysates (35ug/lane).
Image no. 3 for anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 126-151) antibody (ABIN5534758) TRADD Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded ...