FBXW4 antibody (F-Box and WD Repeat Domain Containing 4) (AA 341-370)

Details for Product anti-FBXW4 Antibody No. ABIN5536095
Antigen
  • dac
  • hag
  • hagoromo
  • wu:fk63g06
  • FBXW4
  • DAC
  • FBW4
  • FBWD4
  • SHFM3
  • SHSF3
  • Dac
  • Fbw4
  • dactylin
  • dactylyn
  • F-box and WD repeat domain containing 4
  • F-box and WD-40 domain protein 4
  • fbxw4
  • FBXW4
  • Fbxw4
Epitope
AA 341-370, C-Term
22
15
4
2
2
2
1
1
1
1
1
Reactivity
Human
71
30
29
5
4
4
4
4
3
2
2
1
Host
Rabbit
68
3
Clonality
Polyclonal
Conjugate
This FBXW4 antibody is un-conjugated
6
6
5
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
44
37
20
13
6
3
3
1
Options
Immunogen This FBXW4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the C-terminal region of human FBXW4.
Isotype Ig Fraction
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Plasmids, Primers & others Plasmids, Primers & others FBXW4 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name FBXW4 (FBXW4 Antibody Abstract)
Background This gene is a member of the F-box/WD-40 gene family, which recruit specific target proteins through their WD-40 protein-protein binding domains for ubiquitin mediated degradation. In mouse, a highly similar protein is thought to be responsible for maintaining the apical ectodermal ridge of developing limb buds, disruption of the mouse gene results in the absence of central digits, underdeveloped or absent metacarpal/metatarsal bones and syndactyly. This phenotype is remarkably similar to split hand-split foot malformation in humans, a clinically heterogeneous condition with a variety of modes of transmission. An autosomal recessive form has been mapped to the chromosomal region where this gene is located, and complex rearrangements involving duplications of this gene and others have been associated with the condition. A pseudogene of this locus has been mapped to one of the introns of the BCR gene on chromosome 22.
Molecular Weight 46 kDa
Gene ID 6468
UniProt P57775
Application Notes For WB starting dilution is: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.42 mg/mL
Buffer Supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Supplier Images
Image no. 1 for anti-F-Box and WD Repeat Domain Containing 4 (FBXW4) (AA 341-370), (C-Term) antibody (ABIN5536095) Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
Did you look for something else?