HIST2H2AA4 antibody (C-Term)

Catalog No. ABIN5536908

Product Details anti-HIST2H2AA4 Antibody

Target: HIST2H2AA4 (Histone Cluster 2, H2aa4 (HIST2H2AA4))

Binding Specificity: AA 102-130, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST2H2AA4 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HIST2H2AA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the C-terminal region of human HIST2H2AA4.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for HIST2H2AA4

Target: HIST2H2AA4 (Histone Cluster 2, H2aa4 (HIST2H2AA4))

Alternative Name: HIST2H2AA4 (HIST2H2AA4 Products)

Synonyms: H2A/R antibody, histone cluster 2 H2A family member a4 antibody, HIST2H2AA4 antibody

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the telomeric copy.

Molecular Weight: 14 kDa

Gene ID: 723790, 8337

UniProt: Q6FI13

Pathways: Telomere Maintenance