Histone Cluster 2, H2aa4 (HIST2H2AA4) (AA 102-130), (C-Term) antibody

Details for Product No. ABIN5536908
Target
Binding Specificity
AA 102-130, C-Term
14
8
1
Reactivity
Human
17
1
1
Host
Rabbit
17
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
17
15
1
Options
Immunogen This HIST2H2AA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the C-terminal region of human HIST2H2AA4.
Isotype Ig Fraction
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Target
Alternative Name HIST2H2AA4 (HIST2H2AA4 Antibody Abstract)
Background Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the telomeric copy.
Molecular Weight 14 kDa
Gene ID 723790, 8337
UniProt Q6FI13
Pathways Telomere Maintenance
Application Notes For WB starting dilution is: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Images
Image no. 1 for anti-Histone Cluster 2, H2aa4 (HIST2H2AA4) (AA 102-130), (C-Term) antibody (ABIN5536908) Western blot analysis in K562 cell line lysates (35ug/lane).