Pseudouridylate Synthase 10 (PUS10) (AA 52-78), (N-Term) antibody

Details for Product No. ABIN5537983
Antigen
Epitope
AA 52-78, N-Term
15
7
2
1
Reactivity
Human
45
28
19
2
2
2
2
2
2
1
1
1
1
1
Host
Rabbit
45
Clonality
Polyclonal
Conjugate
Un-conjugated
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Western Blotting (WB)
28
19
13
5
3
1
Options
Immunogen This PUS10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-78 amino acids from the N-terminal region of human PUS10.
Isotype Ig Fraction
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Antigen
Alternative Name PUS10 (PUS10 Antibody Abstract)
Background Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).[supplied by OMIM].
Molecular Weight 60 kDa
Gene ID 150962
UniProt Q3MIT2
Application Notes For WB starting dilution is: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Supplier Images
Image no. 1 for anti-Pseudouridylate Synthase 10 (PUS10) (AA 52-78), (N-Term) antibody (ABIN5537983) Western blot analysis in A549 cell line lysates (35ug/lane).