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Pseudouridylate Synthase 10 (PUS10) (AA 52-78), (N-Term) antibody Primary Antibody

PUS10 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5537983
$570.63
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400 μL
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  • Target
    Pseudouridylate Synthase 10 (PUS10)
    Binding Specificity
    AA 52-78, N-Term
    • 15
    • 8
    • 2
    • 1
    Reactivity
    Human
    • 37
    • 21
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Host
    Rabbit
    • 37
    Clonality
    Polyclonal
    • 37
    Conjugate
    Un-conjugated
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Western Blotting (WB)
    • 25
    • 17
    • 13
    • 3
    • 3
    • 1
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PUS10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-78 amino acids from the N-terminal region of human PUS10.
    Isotype
    Ig Fraction
  • Application Notes
    For WB starting dilution is: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    Pseudouridylate Synthase 10 (PUS10)
    Alternative Name
    PUS10 (PUS10 Antibody Abstract)
    Synonyms
    CCDC139, DOBI, 2810013G11Rik, 4933435A13Rik, AU014648, C77560, Ccdc139, RGD1306402, pseudouridylate synthase 10, PUS10, Pus10
    Background
    Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).[supplied by OMIM].
    Molecular Weight
    60 kDa
    Gene ID
    150962
    UniProt
    Q3MIT2
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