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LRRC32 antibody

LRRC32 Reactivity: Human WB, FACS, IP, EIA Host: Mouse Monoclonal GARP5 unconjugated
Catalog No. ABIN5541855
  • Target See all LRRC32 Antibodies
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    Reactivity
    • 23
    • 9
    • 8
    • 1
    Human
    Host
    • 21
    • 9
    • 1
    • 1
    Mouse
    Clonality
    • 22
    • 10
    Monoclonal
    Conjugate
    • 18
    • 6
    • 3
    • 2
    • 2
    • 1
    This LRRC32 antibody is un-conjugated
    Application
    • 15
    • 14
    • 14
    • 7
    • 3
    • 2
    • 2
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes GARP / LRRC32, an approximately 80 kDa glycoprotein expressed e.g. on the surface of megakaryocytes, platelets and activated Treg cells.
    Purification
    Protein-A affinity chromatography
    Immunogen
    Purified human sGARP protein
    Clone
    GARP5
    Isotype
    IgG1
    Top Product
    Discover our top product LRRC32 Primary Antibody
  • Application Notes
    Flow cytometry. Immunoprecipitation. Western blot. ELISA.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Target
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    Alternative Name
    lrrc32,garp (LRRC32 Products)
    Background
    GARP (glycoprotein A repetitions predominant protein), also known as Garpin or LRRC32 (leucin-rich repeat containing protein 32) is an approximately 80 kDa transmembrane glycoprotein detected on the surface of megakaryocytes, platelets, and activated Treg cells. It binds to the latency-associated peptide (LAP) domain of pro-TGF beta and regulates its storage and activation. The expression of GARP on Treg cells seems to be necessary for their suppressive functions.
    UniProt
    Q14392
    Pathways
    Activated T Cell Proliferation
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