LRRC32 antibody (Leucine Rich Repeat Containing 32)

Details for Product anti-LRRC32 Antibody No. ABIN5541855
Target
Reactivity
Human
14
9
7
1
Host
Mouse
14
6
1
1
Clonality (Clone)
Monoclonal ()
Conjugate
This LRRC32 antibody is un-conjugated
4
3
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
11
9
8
6
3
2
Options
Immunogen Purified human sGARP protein
Clone GARP5
Isotype IgG1
Specificity This antibody recognizes GARP / LRRC32, an approximately 80 kDa glycoprotein expressed e.g. on the surface of megakaryocytes, platelets and activated Treg cells.
Purification Protein-A affinity chromatography
Target
Alternative Name lrrc32,garp (LRRC32 Antibody Abstract)
Background GARP (glycoprotein A repetitions predominant protein), also known as Garpin or LRRC32 (leucin-rich repeat containing protein 32) is an approximately 80 kDa transmembrane glycoprotein detected on the surface of megakaryocytes, platelets, and activated Treg cells. It binds to the latency-associated peptide (LAP) domain of pro-TGF beta and regulates its storage and activation. The expression of GARP on Treg cells seems to be necessary for their suppressive functions.
UniProt Q14392
Pathways Activated T Cell Proliferation
Application Notes Flow cytometry. Immunoprecipitation. Western blot. ELISA.
Restrictions For Research Use only
Format Liquid
Buffer Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
Expiry Date 12 months