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LRRC32 antibody

LRRC32 Reactivity: Human WB, FACS, IP, EIA Host: Mouse Monoclonal GARP5 unconjugated
Catalog No. ABIN5541855
  • Target See all LRRC32 Antibodies
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    Reactivity
    • 26
    • 10
    • 9
    • 1
    Human
    Host
    • 20
    • 12
    • 1
    • 1
    Mouse
    Clonality
    • 21
    • 13
    Monoclonal
    Conjugate
    • 18
    • 7
    • 4
    • 2
    • 2
    • 1
    This LRRC32 antibody is un-conjugated
    Application
    • 16
    • 15
    • 14
    • 6
    • 3
    • 3
    • 2
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes GARP / LRRC32, an approximately 80 kDa glycoprotein expressed e.g. on the surface of megakaryocytes, platelets and activated Treg cells.
    Purification
    Protein-A affinity chromatography
    Immunogen
    Purified human sGARP protein
    Clone
    GARP5
    Isotype
    IgG1
    Top Product
    Discover our top product LRRC32 Primary Antibody
  • Application Notes
    Flow cytometry. Immunoprecipitation. Western blot. ELISA.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Target
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    Alternative Name
    lrrc32,garp (LRRC32 Products)
    Synonyms
    D11S833E antibody, GARP antibody, AI426318 antibody, D11S833Eh antibody, D7H11S833E antibody, EG434215 antibody, Garp antibody, leucine rich repeat containing 32 antibody, LRRC32 antibody, Lrrc32 antibody
    Background
    GARP (glycoprotein A repetitions predominant protein), also known as Garpin or LRRC32 (leucin-rich repeat containing protein 32) is an approximately 80 kDa transmembrane glycoprotein detected on the surface of megakaryocytes, platelets, and activated Treg cells. It binds to the latency-associated peptide (LAP) domain of pro-TGF beta and regulates its storage and activation. The expression of GARP on Treg cells seems to be necessary for their suppressive functions.
    UniProt
    Q14392
    Pathways
    Activated T Cell Proliferation
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