NR1I2 antibody (AA 1-142)
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- Target See all NR1I2 Antibodies
- NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))
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Binding Specificity
- AA 1-142
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This NR1I2 antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- NR1I2 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human NR1I2 (AA:1-142) expressed in E. Coli.
- Clone
- 6H11D8
- Isotype
- IgG1
- Top Product
- Discover our top product NR1I2 Primary Antibody
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anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (AA 101-150) antibody
NR1I2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (AA 100-127) antibodyNR1I2 Reactivity: Human WB, FACS, IHC (p), IF Host: Rabbit Polyclonal RB21890 unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (AA 1-142) antibodyNR1I2 Reactivity: Human ELISA, FACS, ICC Host: Mouse Monoclonal 1D12G1 unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (C-Term) antibodyNR1I2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (AA 51-150) antibodyNR1I2 Reactivity: Human, Mouse, Pig WB, ELISA, FACS, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (AA 1-434) antibodyNR1I2 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (Internal Region) antibodyVerified NR1I2 Reactivity: Human WB, ELISA, IHC Host: Goat Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (AA 279-378) antibodyNR1I2 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (AA 1-434) antibodyNR1I2 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2) (AA 108-157) antibodyNR1I2 Reactivity: Human WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))
- Alternative Name
- NR1I2 (NR1I2 Products)
- Background
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Description: This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.
Aliases: BXR, PAR, PRR, PXR, SAR, SXR, ONR1, PAR1, PAR2, PARq
- Molecular Weight
- 49.8kDa
- Gene ID
- 8856
- HGNC
- 51529
- UniProt
- O75469
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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