KPNA2 antibody (AA 1-530)
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- Target See all KPNA2 Antibodies
- KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
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Binding Specificity
- AA 1-530
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This KPNA2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Purpose
- KPNA2 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human KPNA2 (AA: 1-530) expressed in E. Coli.
- Clone
- 1E8B7
- Isotype
- IgG1
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anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (AA 2-285) antibody
KPNA2 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (C-Term) antibodyVerified KPNA2 Reactivity: Human, Rat WB, IHC, ELISA, IF, FACS Host: Goat Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (C-Term) antibodyKPNA2 Reactivity: Human WB, IF, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (AA 1-290) antibodyKPNA2 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (AA 157-412) antibodyKPNA2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (AA 157-412) antibodyKPNA2 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C18 unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) antibodyKPNA2 Reactivity: Human, Mouse, Rat WB, IHC, IF, IC Host: Rabbit Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (C-Term) antibody (Biotin)Verified KPNA2 Reactivity: Human WB, ELISA, IF Host: Goat Polyclonal Biotin
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (AA 420-528) antibodyKPNA2 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2) (AA 323-372) antibodyKPNA2 Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Monkey WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- KPNA2 (Karyopherin alpha 2 (RAG Cohort 1, Importin alpha 1) (KPNA2))
- Alternative Name
- KPNA2 (KPNA2 Products)
- Background
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Description: The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination.
Aliases: QIP2, RCH1, IPOA1, SRP1alpha
- Molecular Weight
- 58kDa
- Gene ID
- 3838
- HGNC
- 3838
- UniProt
- P52292
- Pathways
- M Phase, Protein targeting to Nucleus
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